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  • Title: Thyroid function and affective illness: a reappraisal.
    Author: Joffe RT, Roy-Byrne PP, Udhe TW, Post RM.
    Journal: Biol Psychiatry; 1984 Dec; 19(12):1685-91. PubMed ID: 6440600.
    Abstract:
    It has been generally accepted that increased thyroid function facilitates treatment response in depression. Recent data show that response to several antidepressant treatments, particularly lithium and carbamazepine, are associated with decreased thyroid hormone levels. An alternative hypothesis that decreased thyroid indices are related to antidepressant response is proposed and clinical and research implications are discussed.
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