These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Canine and feline thyroid function assessment with the thyrotropin-releasing hormone response test.
    Author: Lothrop CD, Tamas PM, Fadok VA.
    Journal: Am J Vet Res; 1984 Nov; 45(11):2310-3. PubMed ID: 6441487.
    Abstract:
    A canine and feline pituitary-thyroid function test based on thyrotropin-releasing hormone (TRH) stimulation of endogenous thyrotropin is described. Serum thyroxine is measured before and after stimulation with TRH. A positive response to TRH indicated a functionally intact pituitary-thyroid axis. At TRH doses of 0.002 to 10.0 mg/kg of body weight, dose response of serum thyroxine to TRH stimulation was determined. Increasing the dose of TRH increased the duration, but not the magnitude, of thyroxine stimulation. At TRH doses greater than 0.1 mg/kg, drug side effects were salivation, defecation, urination, vomition, miosis, tachycardia, and tachypnea. A useful procedure for pituitary-thyroid function testing was serum thyroxine measurement before and 6 hours after TRH (0.1 mg/kg) stimulation.
    [Abstract] [Full Text] [Related] [New Search]