These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Acute hypotensive effect of a central dopaminergic agonist, piribedil, administered intravenously in the normotensive human].
    Author: Ziegler M, Georgiadis G, Elghozi JL.
    Journal: Arch Mal Coeur Vaiss; 1984 Oct; 77(11):1186-90. PubMed ID: 6441537.
    Abstract:
    Ten normotensive patients including 5 parkinsonian and 5 dystonic patients received 3 mg piribedil intravenously over a 15 min period. This dopamine receptor agonist rapidly induced a fall in blood pressure together with a simultaneous reduction in heart rate and temperature. No change was observed when patients (four) were pretreated with a dopamine receptor blocking agent, haloperidol. It is concluded that acute dopamine receptor stimulation leads to a decrease in blood pressure. The hypotension could be centrally-mediated since the hypothermia, considered to be central in origin, parallels the blood pressure and heart rate changes.
    [Abstract] [Full Text] [Related] [New Search]