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  • Title: beta-Mannosidase in human leukocytes and fibroblasts.
    Author: Panday RS, van Diggelen OP, Kleijer WJ, Niermeijer MF.
    Journal: J Inherit Metab Dis; 1984; 7(4):155-6. PubMed ID: 6441861.
    Abstract:
    In human leukocytes and fibroblasts beta-mannosidase activity has a unimodal pH optimum (4.0-4.5). Markedly reduced activity is found in I-cell disease. Normal activities in human fibroblasts are ten times higher than in the goat, in which species a deficiency disease has been described.
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