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  • Title: The management of musculoskeletal problems in hemophilia. Part I. Principles of medical management of hemophilia.
    Author: McMillan CW, Greene WB, Blatt PM, White GC, Roberts HR.
    Journal: Instr Course Lect; 1983; 32():210-6. PubMed ID: 6443730.
    Abstract:
    Musculoskeletal bleeding in general and arthropathy in particular are the central problems among many in the two major forms of hemophilia: classic hemophilia, caused by factor VIII deficiency, and Christmas disease, caused by factor IX deficiency. Currently available replacement therapy, if properly used in a multidisciplinary setting, should provide significant benefit to hemophilic patients despite its cost and occasional complications.
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