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  • Title: Ammonia encephalopathy secondary to urinary tract infection with Proteus mirabilis.
    Author: Samtoy B, DeBeukelaer MM.
    Journal: Pediatrics; 1980 Feb; 65(2):294-7. PubMed ID: 6444460.
    Abstract:
    Hyperammonemia with coma, tachypnea, and respiratory alkalosis developed in a 3-year-old boy with prune"-belly syndrome during a urinary tract infection with Proteus mirabilis. Hyperammonemia is thought to have resulted from the production within the massively dilated urinary tract of excessive amounts of ammonia due to bacterial urease, and its subsequent reabsorption into the systemic circulation. The patient rapidly improved following parenteral antibiotic therapy and continuous catheter drainage of the urinary tract.
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