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Title: Centronuclear myopathy: extraocular- and limb-muscle findings in an adult. Author: Bergen BJ, Carry MP, Wilson WB, Barden MT, Ringel SP. Journal: Muscle Nerve; 1980; 3(2):165-71. PubMed ID: 6445039. Abstract: Myotube-like structures were seen in extraocular and limb muscles in an adult with centronuclear myopathy. The limb-muscle fibers were very small and were of a uniform histochemical type. Extrajunctional acetylcholine receptors were not seen with immunoperoxidase stains, and ultrastructurally normal neuromuscular junctions were seen in the extraocular-muscle samples. Further studies on developing muscle are needed to identify possible mechanisms of arrest of muscle maturation.[Abstract] [Full Text] [Related] [New Search]