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  • Title: [Effects of 5 alpha-androstane-3 beta, 17 beta-diol on release of luteinizing hormone (LH) from 36-38 day old male and female rat anterior pituitaries perifused with constant amounts of gonadotrophin releasing hormone (Gn-GH)].
    Author: Rault B, Girre A, Gaubicher J.
    Journal: C R Seances Soc Biol Fil; 1980; 173(6):1133-41. PubMed ID: 6446367.
    Abstract:
    In vitro (perifusion of rat pituitaries) the 5 alpha-androstane-3 beta, 17 beta diol (3 beta diol) exerts inhibitory effects on Gn-RH stimulated LH secretion. The 3 beta diol is more potent at high dose (1 micrograms/ml) than low dose (100 ng/ml) and in the male rat than in the female rat.
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