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  • Title: [Keratosis palmaris et plantaris areata Siemens. Therapeutic experiments with aromatic retinoid Ro 10-9359].
    Author: Luderschmidt C, Plewig G.
    Journal: Hautarzt; 1980 Feb; 31(2):96-9. PubMed ID: 6447125.
    Abstract:
    A family is presented with keratosis palmoplantaris areata Siemens in four generations. The hyperkeratotic plaques did not responds satisfactorily to treatment with aromatic retinoid Ro 10-9359. Therapy had to be discontinued because of side-effects. Proliferation-retention hyperkeratosis without epidermolytic features may not respond properly to aromatic retinoid treatment.
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