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  • Title: Serotoninergic modulation of mesolimbic and frontal cortical dopamine neurons.
    Author: Waldmeier PC.
    Journal: Experientia; 1980 Sep 15; 36(9):1092-4. PubMed ID: 6448165.
    Abstract:
    Potentiation of the effect of haloperidol on dopamine metabolism by the 5-HT uptake inhibitor CGP 6085 A, and antagonism of this effect by the 5-HT antagonist mianserin were observed in the mesolimbic area and the frontal cortex of the rat brain. A similar effect was reported earlier in the corpus striatum. This suggests that serotoninergic modulation of dopamine neurons is a generally-occurring phenomenon in the brain.
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