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  • Title: Comparison of the glucosyltransferases of Streptococcus mutans gs-5 to a non-cariogenic mutant.
    Author: Bozzola JJ, Johnson MC, Shechmeister IL.
    Journal: J Dent Res; 1980 Oct; 59(10):1613-9. PubMed ID: 6448269.
    Abstract:
    The extracellular glucosyltransferase (GTF) enzymes of Streptococcus mutans GS-5 and avirulent mutant GS-511 were fractionated using agarose and DEAE-cellulose columns. GTF of GS-5 produced both water-soluble and -insoluble glucans, while those of GS-511 made soluble products almost exclusively. Nearly all (98%) of the small amount of insoluble GTF enzyme made by GS-511 was bound to the cell wall.
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