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  • Title: [Gold therapy in chronic polyarthritis. Differentiation of allergic and toxic side effects].
    Author: Bene E, Megyeri A, Györi J.
    Journal: Z Rheumatol; 1980; 39(3-4):109-16. PubMed ID: 6448525.
    Abstract:
    The data from 310 patients treated with gold were analysed. The occurrence of side effects is lower than the average data in the literature: with "Solganal" 21.5%, with "Tauredon" 21%. The clinical importance of the differentiation of toxic and allergic side effects is pointed out. It seems possible to differentiate between the toxic-allergic and the dosage dependent, actually toxic side effects. In cases of toxicity caused by retarded metabolisation the use of the barbiturate enzyme induction made it possible to continue treatment.
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