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  • Title: [Blood serum protein study in oncological patients].
    Author: Gutman EKh, Plaudé RK, Pirogova TF, Vorob'eva LF.
    Journal: Vopr Onkol; 1978; 24(3):68-72. PubMed ID: 644967.
    Abstract:
    The authors report the data on the protein spectrum of blood serum, examined by DEP method in PAAG in 21 patients with ovarian and endometrial cancer and in 20 female-donors. Totally 27 fractions were obtained. The following differences in proteinographs of the groups under examination were revealed: protein in the patients was reliably decreased by 30-90% in the 4th, 9th, 26th fractions, and it was increased by 25-100% in the 15th, 16th, 18th and 22d fractions; 62 patients showed the fraction with Rt 2.10 in the prealbumin zone, which was usually absent in donor blood serum. Moreover, proteinographs from patients with malignant neoplasms of different locatization were studied comparatively. It is believed that the differnces revealed may be used for diagnostic purposes.
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