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  • Title: [Estimation of 131I-Iodohippurate-clearance by a simplified method using a single plasma sample (author's transl)].
    Author: Botsch H, Golde G, Kampf D.
    Journal: Rofo; 1980 Jun; 132(6):713-5. PubMed ID: 6450138.
    Abstract:
    Theoretical volumes calculated from the reciprocal of the plasma concentration after intravenous injection of 131I-Iodohippurate were compared in 95 patients with clearance values calculated by the 2-compartment-method and in 18 patients with conventional PAH-clearance. For estimating Hippurate-clearance from a single blood sampling the most favorable time is 45 min. after injection (r = 0.96; clearance < 400/ml/min.: r = 0.98). Clearance values may be derived from the formula: C = 0.4 + 7.26 V - 0.021 . V2 (V = injected activity/activity per l plasma taken 45 min. after injection). The simplicity, precision and reproducibility of the above mentioned clearance-method is emphazised.
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