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  • Title: [Left ventricular hypertrophy. Correlation of ventriculographic findings in ischemic cardiopathy].
    Author: Gil Moreno M, Cisneros F, Martínez-Ríos MA, Grande F.
    Journal: Arch Inst Cardiol Mex; 1980; 50(5):545-51. PubMed ID: 6451206.
    Abstract:
    In order to analyze the angiographic characteristics associated with left ventricular hypertrophy in patients with coronary insufficiency, the left ventriculography was used to calculate the ventricular volumes, the ejection fraction (EF) and the ventricular mass (LVM) in 31 patients with clinical diagnosis of ischemic heart disease. Patients were divided into three groups: A) Those with normal coronaries and (EF), B) Those with coronary lesion and EF greater than 50% and C) Those with coronary lesions and EF less than 50%. The following results were obtained for the telediastolic volume (ml/m2), the EF (%) and the LUM (g/m2): Group A = 85 +/- 19, 73 +/- 7 and 41 +/- 13. Group B = 102 +/- 25, 61 +/- 8 and 50 +/- 9. Group C = 154 +/- 27, 39 /+- 7 and 74 +/- 17 respectively. Comparing the FEV with the LVM in the patients studied, a negative correlation was found with an r index of -0.7894 (p less than or equal to 0.001). The correlation index for the diastolic volume and the LVM was r = 0.6806; and -0.6991 for the EF and the telediastolic volume. These findings suggest that hemodinamic changes, especially an increase in the ventricular volume and subsequently in the tension of the ventricular wall, act as a stimulus in initiating a metabolic chain leading to ventricular hypertrophy. This process is compensatory in the initial phases of the disease (groups A and B) but insufficient in the advanced stage (group C).
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