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  • Title: [Differences in the properties of specific T-suppressors and cytotoxic T-lymphocytes immune to H-2 complex antigens].
    Author: Abronina IF, Karaulov AV, Brondz BD.
    Journal: Biull Eksp Biol Med; 1980 Dec; 90(12):703-5. PubMed ID: 6451245.
    Abstract:
    Intravenous immunization of mice with a large dose of gamma-irradiated allogenic spleen cells gives rise to specific suppressor T cells and cytotoxic lymphocytes (CTL). However, being optimal form suppressor T cell induction, these conditions of immunization are not conducive to identification of CTL unless they are enriched by elution from the allogenic target monolayer. Unlike CTL, specific suppressor T cells are highly susceptible to gamma-irradiation while their precursors differ from those of CTL by high susceptibility to cyclophosphamide and hydrocortisone.
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