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  • Title: [Clinical studies of cefoperazone in pediatric field (author's transl)].
    Author: Aoyama R, Kuronuma T, Nagata K, Izumi Y.
    Journal: Jpn J Antibiot; 1980 Aug; 33(8):799-802. PubMed ID: 6451727.
    Abstract:
    Clinical studies of cefoperazone (CPZ) were performed and the following results were obtained. 1) CPZ was intravenously administered at the daily dose of 35 approximately 107 mg/kg to 10 children with infection: urinary tract infection (6 cases), respiratory infection (3 cases), and acute enterocolitis (1 case). The overall efficacy rate was 80%, and in urinary tract infection including one case caused by Pseudomonas aeruginosa, efficacy rate was 100%. 2) The bloody stools were noted in one case, 2 days after the administration of CPZ, but improved gradually. No abnormal laboratory data were found.
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