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  • Title: [Clinical examination of cefoperazone in pediatrics (author's transl)].
    Author: Matsuda H, Yoshida T, Kagata N, Niino S.
    Journal: Jpn J Antibiot; 1980 Sep; 33(9):935-40. PubMed ID: 6452543.
    Abstract:
    Clinical studies on cefoperazone (CPZ), a new cephalosporin, were carried out at our department. Seventeen children wih the following bacterial infections were treated with CPZ; pneumonia (7), bronchitis (6), tonsillitis (1), sepsis (2) and purulent meningitis (1). The dosage was 56 approximately 182 mg/kg/day, divided into 4 doses, and given intravenous injection. The duration of administration was from 4 to 15 days. Clinical results were excellent in 3 cases, good in 9 cases, moderate in 3 cases, poor in 1 case and uncertain in 1 case. The overall efficacy rate was 75.0%. No side effects were observed.
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