These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Rates of chromosome abnormalities at different maternal ages.
    Author: Hook EB.
    Journal: Obstet Gynecol; 1981 Sep; 58(3):282-5. PubMed ID: 6455611.
    Abstract:
    Estimates are made of the rates of all clinically significant cytogenetic abnormalities in live births by 1-year maternal age intervals ranging from 15 to 49. Down syndrome results from the most prevalent clinically significant cytogenetic abnormality, yet the rates of disorders associated with other cytogenetic abnormalities also increase with maternal age and significantly contribute to the overall rate at the older ages. The estimated rate of all clinically significant cytogenetic abnormalities rises from about 2 per 1000 (1 per 500) at the youngest maternal ages to about 2.6 per 1000 (1 per 270) at age 30, 5.6 per 1000 (1 per 80) at age 35, 15.8 per 1000 (1 per 60) at age 40, and 53.7 per 1000 (1 per 20) at age 45.
    [Abstract] [Full Text] [Related] [New Search]