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  • Title: Neuraminidase production by Propionibacterium acnes-strains isolated from patients with acne vulgaris, seborrheic eczema and healthy subjects.
    Author: Höffler U, Gloor M, von Nicolai H.
    Journal: Zentralbl Bakteriol Mikrobiol Hyg A Med Mikrobiol Infekt Parasitol; 1981; 250(1-2):122-6. PubMed ID: 6458977.
    Abstract:
    Among cutaneous propionibacteria, synthesis of neuraminidase is highest in strains of the species P, acnes. In the present study, neuraminidase activity was discovered in 90.0% of P. acnes strains isolated from acne lesions compared with 72.7% of strains from normal human skin. Neuraminidase-positive strains from acne lesions, moreover, produced statistically significant higher amounts of the enzyme (X = 727 microunits/ml bacterial suspension) than isolates from normal skin (X - 392 microunits/ml). Whereas the moderate production of neuraminidase by strains from patients with seborrheic eczema is probably of no causative importance, the enzyme has to be discussed a potential etiologic factor in acne vulgaris.
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