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  • Title: Huntington's disease: alterations of visual and somatosensory cortical evoked potentials in patients and offspring.
    Author: Oepen G, Doerr M, Thoden U.
    Journal: Adv Neurol; 1982; 32():141-7. PubMed ID: 6459718.
    Abstract:
    In 13 patients suffering form Huntington's chorea (H.Ch.), VEPs and SEPs were investigated in comparison to 9 clinically inconspicuous offspring and normal adults. 1. The mean amplitude of VEP was reduced in choreatic patients and in four out of nine offspring. 2. Latencies of P100 in VEP were normal in all subjects. 3. The late components were reduced in amplitude and rather irregular in shape. 4. The latencies of SEPs were slightly prolonged, less marked in the early peaks and more pronounced in the later ones. 5. The late components after 70 to 100 msec were often attenuated or even absent. 6. The mean amplitude of the first two peaks was reduced. 7. Interhemispheric asymmetries were pronounced in three out of nine offspring.
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