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  • Title: HLA and rheumatoid arthritis. A study of five families.
    Author: Ström H, Möller E.
    Journal: Tissue Antigens; 1981 Aug; 18(2):92-100. PubMed ID: 6461092.
    Abstract:
    Five families with two or more members ill with rheumatoid arthritis were investigated clinically. Tissue typing for HLA A, B, C and D/DR antigens was performed. We could not define may HLA haplotype associated with disease within these families. However, the prevalence of the haplotypes containing HLA-DR4 was high, suggesting a direct relationship between DR4 and increased risk of contracting rheumatoid arthritis.
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