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  • Title: Clinical trial of an oral contraceptive containing desogestrel and ethinyl estradiol.
    Author: Weijers MJ.
    Journal: Clin Ther; 1982; 4(5):359-66. PubMed ID: 6461412.
    Abstract:
    A clinical trial involving 1,159 women who used the tested preparation for a total of 15,222 observed cycles showed an oral contraceptive containing 150 micrograms of desogestrel in combination with 30 micrograms of ethinyl estradiol to be highly effective. Desogestrel is a potent progestogen, which, at the doses used for oral contraception, is devoid of any androgenic activity. Cycle control during the trial was good. No serious side effects occurred, and the incidence of minor complaints was lower than during a nontreated control cycle.
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