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  • Title: Pharmacokinetics of paracetamol in patients with gastric and duodenal ulcers.
    Author: Wójcicki J, Gawrońska-Szklarz B.
    Journal: Pol J Pharmacol Pharm; 1984; 36(1):59-63. PubMed ID: 6462961.
    Abstract:
    Pharmacokinetics of orally applied single dose of paracetamol was studied in patients with gastric ulcer and duodenal ulcer. The course of changes in paracetamol concentration was described using a two-compartment open model for extravascular administration; the calculations were carried out using an Odra 1300 computer. The changes in pharmacokinetics of paracetamol in the patients with gastric and duodenal ulcer was altered: the absorption was increased particularly in patients with duodenal ulcerosis and delayed in patients with both gastric and duodenal ulcers.
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