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  • Title: Halo nevi and melanoma.
    Author: Pellegrini JR, Wagner RF, Nathanson L.
    Journal: Am Fam Physician; 1984 Aug; 30(2):157-9. PubMed ID: 6464957.
    Abstract:
    Halo nevi may be associated with occult melanoma or may signify melanoma in a remote location. When a single halo nevus is present, the lesion should be biopsied to exclude melanoma. In addition, the patient's entire skin surface should be examined, and a careful ophthalmologic examination should be performed to exclude intraocular melanoma. Although the pathophysiologic relationship of halo nevus to melanoma is unclear, immunologic mechanisms have been postulated.
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