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  • Title: Contrasting short- and long-term effects of weight loss on lipoprotein levels.
    Author: Follick MJ, Abrams DB, Smith TW, Henderson LO, Herbert PN.
    Journal: Arch Intern Med; 1984 Aug; 144(8):1571-4. PubMed ID: 6466014.
    Abstract:
    The short- and long-term effects of weight loss on high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol levels were examined in 42 women who completed a 14-session behavioral weight-loss program. Lipid values were determined from samples taken before treatment, after treatment, and at six-month follow-up. There were significant changes in plasma lipid levels, but the short- and long-term effects differed. Both total and LDL cholesterol levels decreased during treatment and remained lower at follow-up. However, HDL cholesterol level and the HDL/LDL ratio did not change during treatment but increased significantly above pretreatment levels at follow-up. Furthermore, long-term changes in lipoprotein levels were significantly correlated with changes in the body-mass index even after correction for initial values. These results show that weight loss can, in the long term, have a potentially beneficial impact on lipoprotein levels in women.
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