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  • Title: [Reactions of Paneth cells of the rat jejunum to section of the vagus nerves (ultrastructural analysis)].
    Author: Eletskiĭ IuK, Kulikova OV, Tsibulevskiĭ AIu.
    Journal: Arkh Anat Gistol Embriol; 1984 Apr; 86(4):73-9. PubMed ID: 6466118.
    Abstract:
    Dynamics of ultrastructural alterations of Paneth cells (PC) of the rat jejunum have been investigated after bilateral subdiaphragmal trunkal vagotomy (7, 14, 30 and 60 days). This operation results in a profound ultrastructural rearrangement in PC organization, which is especially manifested on the 7th and 14th days. The cisterns and canaliculi of the endoplasmic reticulum dilate, the Golgi complex structure is disturbed, the matrix of mitochondria is cleared, their crists are fragmented, large vacuoles with electron transparent contents appear, total amount of the secretory granules and relative number of their immature forms increase, the secreory granules form and topography of their core is changed, small structures resembling microtubules appear in them. Beginning from the second week, morphological alterations of compensatory-adaptive character progressively increase: the number of free ribosomes grows large and large mitochondria appear.
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