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  • Title: [Formation of endogenous pyrogen by mononuclear phagocytes].
    Author: Agasarov LG, Sorokin AV, Ukhanova IK.
    Journal: Biull Eksp Biol Med; 1984 Jul; 98(7):24-6. PubMed ID: 6466820.
    Abstract:
    Production of endogenous pyrogen by human and rabbit blood monocytes in response to stimulation with agents of different origin was studied by inhibitory analysis under comparable conditions. Actinomycin D and cytochalasin B were applied. New evidence was obtained about an important role in the mechanism of activation of mononuclear phagocytes of initial interaction between a stimulating agent and the leukocyte membrane and of the biphasic process of endogenous pyrogen production.
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