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  • Title: [Absorption by rat fetal tissues of 14C-labeled phospholipids injected into the rat body in the late stages of pregnancy].
    Author: Aĭlamazian EK, Taranova NP, Zhuravlev AV, Kirchik OS.
    Journal: Biull Eksp Biol Med; 1984 Jul; 98(7):93-4. PubMed ID: 6466841.
    Abstract:
    The authors studied the possibility of 14C-phospholipid transplacental penetration after 15C-phospholipid injection into rats at the 20th day of pregnancy. The preparation of 14C-phospholipids (total phospholipids) was isolated by thin-layer chromatography from the liver of rats injected with 2-14C-sodium acetate. One hour after its injection into the rat, 14C-phospholipids were detectable in total phospholipids of the pulmonary and cerebral fetal tissues. It was discovered that specific radioactivity of phospholipids contained by these tissues was 2--5 times higher when 14C-phospholipids were injected subcutaneously as compared with intramuscular injection. It is concluded that exogenous phospholipids entrapped in the mother's circulation penetrate the placental barrier of the fetus and the blood-brain barrier of the mature fetus, being consumed by different fetal tissues for forming membrane structures of the fetal tissues.
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