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  • Title: Antiviral therapy in HBsAg-positive chronic liver disease (HBsAg+ve CLD): how many patients really need it?
    Author: Ascione A, Amitrano L, Riccio E, De Lella A, Canestrini C, de Bellis G, D'Alessandro R, Fiore R, Padulano P.
    Journal: Hepatogastroenterology; 1984 Jun; 31(3):123-4. PubMed ID: 6469200.
    Abstract:
    One hundred and seventy-one consecutive patients with HBsAg+ve CLD were investigated in order to assess whether they were actively replicating the hepatitis B virus, and therefore eligible for antiviral therapy. Our results show that only 5.8% of patients were actively replicating B virus and therefore antiviral therapy, when available, could be used only for a small subgroup of patients suffering from CLD due to hepatitis B virus chronic infection.
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