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  • Title: Dexamethasone suppression test and treatment response.
    Author: Gitlin MJ, Gwirtsman H, Fairbanks L, Sternbach HA, Cedars PI, Gerner RH.
    Journal: J Clin Psychiatry; 1984 Sep; 45(9):387-9. PubMed ID: 6469923.
    Abstract:
    The dexamethasone suppression test (DST) is frequently used to predict response to antidepressant therapy or to noradrenergic vs. serotonergic antidepressants. In a study of 173 inpatients and outpatients, the DST was not found to be predictive of response to antidepressant treatment for all depressed patients or of treatment response in a subgroup of melancholic patients (N = 86). Response of DST suppressors and nonsuppressors to antidepressants stratified by neurotransmitter specificity was not found to differ.
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