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  • Title: Influence of glycaemic normalisation by an artificial pancreas on phagocytic and bactericidal functions of granulocytes in insulin dependent diabetic patients.
    Author: Gin H, Brottier E, Aubertin J.
    Journal: J Clin Pathol; 1984 Sep; 37(9):1029-31. PubMed ID: 6470179.
    Abstract:
    Ten insulin dependent diabetic patients were maintained in normoglycaemia for 36 h with an artificial pancreas. Circulating polymorphonuclear leucocytes were extracted and incubated with staphylococcus before and after treatment; phagocytic and bactericidal activities were studied. Granulocytes from diabetic patients showed a decreased ability to absorb staphylococcus and a reduced capacity for intracellular destruction of bacteria. These two functions were improved after 36 h of normoglycaemia but were not corrected.
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