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  • Title: Electrophoretic patterns of proteins in cystic fibrosis sweat.
    Author: Penneys NS, Haft J, Rubin R.
    Journal: J Invest Dermatol; 1984 Sep; 83(3):238-9. PubMed ID: 6470527.
    Abstract:
    The abnormal gene product in cystic fibrosis has not been identified. We report that two-dimensional polyacrylamide gel electrophoresis of 125I-labeled sweat proteins coupled with fluorography and rare earth screen radioautography reveals an absence of an acidic protein of molecular weight 60,000 in sweat collected from 9 patients with cystic fibrosis. The protein spot was present in sweat from heterozygotes and from controls.
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