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  • Title: [Incidence, laboratory diagnosis and serologic prediction of hemolytic disease of newborn infants due to ABO incompatibility].
    Author: Schönitzer D, Frisch H.
    Journal: Padiatr Padol; 1984; 19(3):263-78. PubMed ID: 6472867.
    Abstract:
    The frequency of the haemolytic disease of the newborn due to ABO-incompatibility (ABO-HDN), requiring treatment, is with approximately 5% of all hyperbilirubinemias in newborns lower than usually expected. Contrary to common conception the serologic diagnosis of ABO-HDN by means of the direct antiglobulin test (DAT) is possible with satisfactory accuracy. The enormous laboratory burden of IgG-anti-A, -B testing during pregnancy is in poor conformity with clinically demonstrable illness. This discrepancy is due to the rarity of true ABO incompatibilities and not to the ineffectiveness of laboratory investigations.
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