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Title: Efficacy of triclabendazole against Fasciola hepatica and Fascioloides magna in naturally infected calves. Author: Craig TM, Huey RL. Journal: Am J Vet Res; 1984 Aug; 45(8):1644-5. PubMed ID: 6476577. Abstract: Twenty calves (8 to 12 months old), naturally infected with Fasciola hepatica and Fascioloides magna, were obtained from Brazoria, Tex. They were randomly allotted to 3 treatment groups. One group (6 calves) was given the carrier without drug, the 2nd group (7 calves) was treated with triclabendazole at 6 mg/kg of body weight, and the 3rd group (7 calves) was treated with triclabendazole at 12 mg/kg. All treatments were administered as a drench. Calves given triclabendazole (either dosage level) had a 100% reduction in F hepatica burden as compared with the untreated controls. Both treatment doses also appeared to have detrimental effect on F magna infections. Viability of all flukes was determined on the basis of movement, color, and tegumental integrity. Clinical toxic reactions were not observed in the treated calves.[Abstract] [Full Text] [Related] [New Search]