These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Anesthesia selectively reduces hypoglossal nerve activity by actions upon the brain stem.
    Author: Bennett FM, St John WM.
    Journal: Pflugers Arch; 1984 Aug; 401(4):421-3. PubMed ID: 6483584.
    Abstract:
    Alcohol as well as anesthetic and sedative agents depress the respiratory activity of the hypoglossal-genioglossal system more than that of the phrenic-diaphragmatic system. The mechanisms for this selective depression remain unclear. To evaluate the contribution of pathways traversing the spinal cord, the response of phrenic and hypoglossal nerve activities to 0.5% halothane was obtained in decerebrate cats before and after transection of the spinal cord at T1 and again following transection at C1. Halothane produced a much greater decrease in hypoglossal than phrenic activity before and after spinal cord section at T1. Following cord section at C1, which eliminates phrenic activity, 0.5% halothane still produced a marked depression of hypoglossal activity. Therefore, the selective depression of the hypoglossal-genioglossal system does not depend on spinal mechanisms and appears to be mediated in the brain stem.
    [Abstract] [Full Text] [Related] [New Search]