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  • Title: Neonatal pancreatic function in infants born to mothers with gestational and overt diabetes.
    Author: de Villiers TJ, Macfarlane CM, Tsakalakos N, Taljaard JJ.
    Journal: S Afr Med J; 1984 Nov 03; 66(18):690-3. PubMed ID: 6495112.
    Abstract:
    Neonatal pancreatic function was assessed in infants born to non-diabetic mothers and to mothers with well-controlled gestational diabetes (GD) and overt diabetes (OD) using cord blood C-peptide estimations and the calculation of cord C-peptide/glucose ratios. Exaggerated pancreatic function was present in infants born to mothers with GD. In these infants the increased cord C-peptide values and cord C-peptide/glucose ratios correlated with their increased birth weight ratios. These results could not be explained on the basis of maternal hyperglycaemia and a possible intrinsic difference in pancreatic response between infants born to mothers with GD and those born to mothers with OD is suggested.
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