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  • Title: [DNA-phospholipid interaction. 31P-NMR study].
    Author: Viktorov AV, Grepachevskiĭ AA, Bergel'son LD.
    Journal: Bioorg Khim; 1984 Jul; 10(7):935-9. PubMed ID: 6497914.
    Abstract:
    The phage T7 DNA complexes with various phospholipids (PL) were studied by 31P NMR at PL/nucleotide molar ratio of 2 : 1. Using a phosphatidylcholine thion analogue, the contributions of PL and DNA into the 31P NMR spectrum of the complex were estimated. It was found that PL-DNA interaction results in partial immobilizing ability of PL depends on their structure, increasing in the following row: phosphatidylcholine-phosphatidylethanolamine less than sphingomyelin less than or equal to ternary mixture of these PL. The data obtained are indicative of nonequivalent binding of DNA with various PL species.
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