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  • Title: [Comparative study of the effect of ethacizin and lidocaine on the blood supply and function of the intact and ischemic myocardium].
    Author: Goldshteĭne GKh, Chichkanov GG.
    Journal: Biull Eksp Biol Med; 1984 Oct; 98(10):466-9. PubMed ID: 6498326.
    Abstract:
    It has been shown in experiments on cats anesthesized with nembutal that lidocaine (1.0 and 2.0 mg/kg) and etacizine (0.5 and 1.0 mg/kg) decrease heart work and create in the heart muscle a definite oxygen reserve, without exerting any inhibitory effect on myocardial contractile function. The drugs improve the function of the focus of myocardial ischemia, with the effect of etacizine being more lasting.
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