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  • Title: [The pituitary-adrenal system in cancer of the esophagus and stomach].
    Author: Tarutinov VI, Ganul VL, Vinnitskiĭ VB, Pridatko OE.
    Journal: Eksp Onkol; 1984; 6(4):55-7. PubMed ID: 6499754.
    Abstract:
    Excretion of corticosteroids, levels of 11-OCS in blood plasma, tests with dexasone and clinical evaluation of the pituitary-adrenal system function were studied in 354 patients with carcinomas of the esophagus and proximal stomach division. Some degree of hypocorticism with a decrease in the 11-OCS level in blood plasma and lowered excretion of corticosteroids in the urine were found in 71% of patients. These variations are accompanied by lowered hypothalamus sensitivity to dexasone. Similar disturbances though less pronounced are determined in the precancerous states and in the remote periods after operation.
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