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  • Title: [A new technic for the sealing of a frontobasal cerebrospinal fluid fistula. Experiences with a hardening alcoholic protamine solution].
    Author: Krähling KH, König HJ.
    Journal: Fortschr Med; 1984 Oct 25; 102(40):1017-8. PubMed ID: 6500462.
    Abstract:
    Fractures of the frontal base of the skull are often accompanied by rhinoliquorrhea. To prevent infections of the brain they must always be closed surgically. We report on a new method of closing the dura mater defect using an alcoholic prolamine solution, which hardens within a few minutes. After 40 to 90 days the mass has been replaced by connective tissue. We describe our experience with 24 patients who were successfully operated on using this method and followed up for two years.
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