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  • Title: Early migration of immature Fasciola hepatica and associated liver pathology in cattle.
    Author: Doy TG, Hughes DL.
    Journal: Res Vet Sci; 1984 Sep; 37(2):219-22. PubMed ID: 6505402.
    Abstract:
    Immature Fasciola hepatica were successfully recovered from the body cavity of cattle from two to 21 days after oral infection. Flukes had penetrated the liver in large numbers by day 7 but there did not appear to be a corresponding reduction in the numbers recovered from the body cavity. Liver pathology showed a typical progressive tissue disruption with a neutrophil and lymphocyte infiltration by day 7 and a marked eosinophil response from day 14. The mesothelium of the liver capsule underwent metaplasia, becoming ultimately highly active and columnar.
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