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  • Title: [Excretion of free and bound catecholamines in the urine of diabetes mellitus patients].
    Author: Vakov L, Orbetsova V.
    Journal: Vutr Boles; 1984; 23(4):72-9. PubMed ID: 6506663.
    Abstract:
    The 24-h excretion of free, conjugated and total fractions of dopa, dopamine, noradrenaline and adrenaline was studied in 32 patients with diabetes mellitus. Adrenaline and dopamine were established to be increased--dopa decreased and noradrenaline--not changed. An attempt is made to explain the hormonal changes on the base of the analysis of the so called synthetic and dissociative coefficients of catecholamines. A moderate reverse correlation of the changes with the age of the patients and duration of diabetes was established as well as lower values in the female-diabetics versus the male-diabetics. The hormonal deviations are associated with the disturbances in the carbohydrate metabolism, have a reactive character and are manifested in insulin-dependent type of diabetes.
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