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  • Title: The effect of a single dose of metrifonate on Schistosoma haematobium infection in Egyptian school children.
    Author: el Kholy A, Boutros S, Tamara F, Warren KS, Mahmoud AA.
    Journal: Am J Trop Med Hyg; 1984 Nov; 33(6):1170-2. PubMed ID: 6507729.
    Abstract:
    Egyptian school children infected with Schistosoma haematobium and treated with a single dose of metrifonate, 10 mg/kg body weight, had a marked reduction in urine egg counts reaching 90% during a 30-week follow-up. While cure rate was higher among lightly infected persons, percentage reduction in egg counts was greater among the heavily infected. After a summer period of probable high risk exposure reinfection rate in those children who were treated and cured was 4.7% as compared to 6% in previously uninfected children.
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