These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Interrelation between the analgesic and ulcerogenic action of cysteamine].
    Author: Vinogradov VA, Polonskiĭ VM, Siutkin EA, Smagin VG.
    Journal: Biull Eksp Biol Med; 1984 Nov; 98(11):582-3. PubMed ID: 6509176.
    Abstract:
    Interrelationship was studied between the influence of cysteamine on pain threshold and ulcerogenic effect on the duodenum. Cysteamine (350 mg/kg) induced analgesia in mice which was prevented by naloxone (1.5 mg/kg). In rats, cysteamine produced duodenal ulcers with concomitant analgesia. The intensity of ulceration was higher in animals with lower basal pain threshold. The correlation between central and peripheral effects of endogenous opioids in the development of experimental duodenal ulcers is discussed.
    [Abstract] [Full Text] [Related] [New Search]