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  • Title: Three-dimensional architecture of altered dermal elastic fibers in pseudoxanthoma elasticum: scanning electron microscopic studies.
    Author: Tsuji T.
    Journal: J Invest Dermatol; 1984 May; 82(5):518-21. PubMed ID: 6512272.
    Abstract:
    The three-dimensional architecture of the altered dermal elastic fibers of patients with pseudoxanthoma elasticum has been demonstrated using a scanning electron microscope. Each of the altered elastic fibers could be divided into three parts: (i) a normal-looking, slender part which is composed of thinner fibrils, (ii) a thickened, tortuous part covered with an amorphous substance, and (iii) a markedly damaged part where calcium is exposed to the surface of the fibers. The presence of calcium and phosphorus in the altered elastic fibers has been proved by an electron x-ray microanalysis.
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