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  • Title: Chemoprophylaxis in major head and neck surgery.
    Author: Raine CH, Bartzokas CA, Stell PM, Gallway A, Corkill JE.
    Journal: J R Soc Med; 1984 Dec; 77(12):1006-9. PubMed ID: 6512802.
    Abstract:
    Wound infections are a significant complication following major oncological head and neck surgery. In view of the controversy surrounding the use of chemoprophylaxis a controlled trial was designed. Intravenous Augmentin (amoxycillin and clavulanic acid) was shown to reduce significantly (P less than 0.025) the incidence of postoperative sepsis.
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