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  • Title: [Clinical studies of cefoxitin with special reference to pulmonary suppuration and pyothorax with respiratory tract infection].
    Author: Ito T.
    Journal: Jpn J Antibiot; 1984 Sep; 37(9):1679-84. PubMed ID: 6512984.
    Abstract:
    Cefoxitin (CFX) was administered to 12 patients with respiratory tract infections, including mainly patients with pulmonary suppuration or pyothorax. The results were as follows: CFX was effective in 75% of the total patients, and in 83% of the 6 patients with pulmonary suppuration or pyothorax. Microorganisms which were considered to be causative were isolated in 8 of 12 patients. Bacteriological responses were "eradicated" in 4 patients, "replaced" in 3 patients, "unchanged" in 1 patient. A slight elevation of S-GPT was observed in one patient and elevation of A1-P in another following CFX administration; however, these values returned to normal shortly after completion of drug administration. No adverse effects, allergic symptoms or laboratory abnormalities were observed.
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