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  • Title: [Evaluation of adaptation of animals to hypoxic hypoxia by the multiple regression method].
    Author: Kustov VV, Litau VG, Kukushkin IuA, Razinkin SM.
    Journal: Kosm Biol Aviakosm Med; 1984; 18(6):67-9. PubMed ID: 6513489.
    Abstract:
    White mice were exposed to hypoxic hypoxia during 30 days. In the study a correlation between the altitude ceiling and various physiological parameters (body weight, body temperature variations in response to a cold stress (5 degrees C), hemoglobin content, coefficients of adaptive oxygen consumption determined as the ratio of oxygen consumption at 6000 m to that at sea level (K1) and the ratio of oxygen consumption in hypoxic environment to that in a normoxic atmosphere (K2) was established. The data obtained allow the conclusion that the multiple regression method can be used for measuring objectively the tension of regulatory systems and for discriminating stages of animal adaptation to hypoxic hypoxia.
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