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  • Title: Retinoblastoma. CT diagnosis.
    Author: Char DH, Hedges TR, Norman D.
    Journal: Ophthalmology; 1984 Nov; 91(11):1347-50. PubMed ID: 6514301.
    Abstract:
    Computed tomography (CT) scan is a valuable adjunct in the differential diagnosis and management of retinoblastoma. Thirty-one of 33 retinoblastoma patients studied with high resolution computed tomography had intraocular calcification demonstrable in at least one eye. Over 80% of tumors showed evidence of calcification on CT scan. The degree of calcification appeared to depend upon tumor size; only small tumors were devoid of calcification. The amount and distribution of calcification was similar on both histological and CT review. In patients under three years of age in whom a retinoblastoma is suspected, the presence of calcification on CT scan is virtually diagnostic of retinoblastoma; patients with leukocoria without calcification on CT probably have a simulating lesion.
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